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	Provedor de dados OAK (1) Autor Asada, Masahito (1) Inoue, Noboru (1) Kawazu, Shin-ichiro (1) Suganuma, Keisuke (1) Yamagishi, Junya (1) Yamasaki, Shino (1) Yokoyama, Naoaki (1) Mais... Palavra-chave Epimastigote (1) Hemoglobin receptor (1) Trypanosome congolense (1) Ano 2016 (1) País Japan (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Characterization of an epimastigote-stage-specific hemoglobin receptor of Trypanosoma congolense OAK Yamasaki, Shino; Suganuma, Keisuke; Yamagishi, Junya; Asada, Masahito; Yokoyama, Naoaki; Kawazu, Shin-ichiro; Inoue, Noboru. Background: Since Trypanosorna spp. lack a complete heme synthesis pathway, the parasites are totally dependent on their host for heme throughout all of the stages of their life -cycle. We herein report the identification and characterization of a T. congolense epimastigote form (EMF)-specific hemoglobin (Hb) receptor. The gene was initially reported to encode a T. congolense haptoglobin (Hp)-Hb complex receptor (TcHpHbR) based on its similarity to a gene encoding a T brucei Hp-Hb complex receptor (TbHpHbR). Methods: Trypanosorna congolense IL3000 was used in this study. A TcHpHbR gene was PCR amplified from the parasite genome. The recombinant protein was used as an immunogen to raise antibodies for immunofluorescence assay and immunoblotting. Hemoglobin... Palavras-chave: Trypanosome congolense; Epimastigote; Hemoglobin receptor. Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4441 Registros recuperados: 1 Primeira ... 1 ... Última

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